160402_OptosDiagAtlasAF

Diagnostic Atlas

A Retinal Reference Guide

Hypoautofluorescence

is a decreased AF signal which will appear black on the image.

Many disease states can cause this retinal damage and a

hypoautofluorescence signal

∙Geographic atrophy

∙Hereditary retinal dystrophies

∙RPE hypertrophy

∙Intraretinal fluid (e.g., macular oedema)

∙Intraretinal and subretinal lipid

∙Fresh intra- and subretinal haemorrhages

∙Fibrosis, scar tissue, or borders of laser scars

∙Retinal Vessels

∙Luteal pigment (lutein and zeaxanthin)

∙Media opacities (vitreous, lens, anterior chamber,

or cornea)

Pigmentary Retinopathy

Retinitis Pigmentosa

Diabetic Retinopathy with Haems

Hypoautofluorescence