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R

n=188

n=178

Surgery

Chemoradiation

surgery

(23x1.8 Gy + 5x weekly carboplatin/paclitaxel)

4-6 weeks

Pre-operative chemoradiation improves outcome in

esophageal and junctional cancer: the CROSS trial

Shapiro et al. Lancet Oncol 2015 (median FU 84.1 months)