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Epidemiology of esophageal cancer
• 2012: Europe ~46,000 cases/year; ~39,500 deaths
• 6
th
leading cause of cancer-related mortality
• 8
th
most common cancer worldwide
• Worldwide >450,000 people are affected
• Incidence is increasing rapidly
• Overall 5-year survival 15-25%
• Diagnosis at advanced (metastatic) stages
• 30-40% present with resectable disease
• SCC is predominant type; in some western European countries
adenocarcinoma exceeds SCC