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Introduction
Radiation therapy affects both tumor cells and uninvolved normal cells
0.8
1.0
y
p
TC
tumor cures
p
NTC
normal tissue
60
70
80
0.0
0.2
0.4
0.6
Probabilit
Dose
complications
p
TC
(1 - p
NTC
)
cures without
complications
Holthusen, 1936