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PTV in practice: oesophagus

Systematic uncertainty

(confidence level)

Σ

(mm)

Σ

2

Snapshot CT

1.32 1.74

Delineation (intra observer)

4.00 16.00

Random uncertainty

(dose blurring)

σ

(mm)

σ

2

Intrafraction organ mobility 1.00 1.00

Interfraction setup (laser)

4.52 20.43

Interfraction setup (laser)

19.13 365.96

Interfraction setup (IGRT)

(intra observer registration)

0.3 0.09

End2end IGRT

(eg PentaCheck)

1.08 1.17

QUADRATIC SUM

384.96

Intrafraction patient motion 1.99 3.96

σ

p

3.2 10.24

QUADRATIC SUM

35.63

σ

5.97

The PTV 2017 - D. Verellen

Σ

19.62

σ

p

3.2

PTV margin (mm)

53.59

M

=

a

S +

b s

2

+

s

p

2

-

bs

p

α=2.5

β=1.64