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“Conventional” IMRT planning

90% prob.

of

D≥95%D

P

in

CTV

M = 2.5

Σ

+ 0.7

σ

CTV PTV

OAR PRV

IMRT optimization

Dose Distribution

Objective Function

(cell kill, EUD, DVH, …)

The PTV 2017 - D. Verellen