453 / 1084
CROSS I & II Trials* 418 patients
Patterns of relapse in Esophageal Cancer
• Most patients had distant failure (22%) or combined locoregional (LRR) and
distant failure (16.5%)
• Isolated locoregional recurrence 9.3% surgery & 3.3% CRT+S
• Majority of LRR developed within 2 years & none after 30 months
Oppedijk V, van der Gaast A, van Lanschot J et al. 2014 JCO doi:10.1200/JCO.2013.51.2186