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7 treatment-associated deaths (16%) in arm A (CDDP+5FU)

“The severe side-effects induced by the combination suggest that,

Oesophageal Cancer

„Standard Therapy“

Bleiberg et al.

Eur J Cancer

1997; 33: 1216-20

currently, no standard chemotherapy can be recommended

for patients with advanced squamous cell oesophageal cancer…“

and

“…chemotherapy should not be

given to patients with advanced squamous cell oesophageal

cancer outside of prospective studies.”