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The Royal Marsden
JCOG 0110 “Splenectomy or Not”
505 patients
Similar operative mortality with or without splenectomy
Greater postoperative morbidity with splenectomy
Greater intraoperative blood loss with splenectomy
5 year survival
Splenectomy
75.1%
Splenic preservation 76.4%
Sano T, et al. J Clin Oncol. 2010;28(15 Suppl):abstract 4020; GI ASCO 2015
.