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Macdonald

281 pts

%

RT-CT compliance

China

186 pts

%

64.0

90.7

Korean

544 pts

%

75.0

Modern radiotherapy

favours less toxicity

Background

and

assumptions:

the challenge

G3 Acute Tox

G4 Acute Tox

41.0

32.0

13.4

Macdonald JS et Al – NEJM -2001

Kim S, Macdonald JS et Al – IJROBP – 2005

Zhu W et Al – Radioth Oncol - 2012

23.5

6.0

EQD2: 44.25 Gy

EQD2: 44.25 Gy

EQD2: 44.25 Gy