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Post-operative

Chemoradiation

• Zhu et al – 2012

Stage T3 or T4 and (or) N positive(M0) 404 pts

D2 5 folowed by FUL vs FUL RT+FU 2FUL

SURVIVAL

LOCAL CONTROL

Zhu

et al

l: Radiot Oncol 2012

(China)

RT (IMRT) : 45 Gy (1.8 Gy fx)

HR 1.24 (95% CI, 0.94–1.65; P = 0.122).

HR 1.35 (95% CI, 1.03–1.78; P = 0.029

EQD2: 44.25 Gy