722 / 1084
Molecular subtypes
1) Chromosomal instable 49,8%
2) Microsatellite-instable 21,7%
3) Genomic stable 19,6%
4) EBV-induced 8,9%
Institute of Pathology | Alexander Quaas
Gastrointestinal Cancer Group Cologne (GCGC)
From: CancerGenomeAtlasResearchNetwork, „comprehensive molecular characterization of gastric adenocarcinoma“ Nature 2014
Microsatellite-instable carcinoma and
EBV-positive carcinoma: more
antigenes/highly inflammed: probably
immunocheckpoint inhibition (and
perhaps radiation) more effective