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Regression-Scores after
neoadjuvant therapy
According to Becker et al:
Morphological regressions signs:
• oedema
• necrosis
• foamy histiocytes
• fibrosis and hyalinosis
Grading of Histophathologic Regression in the Primary Tumor Bed
Institute of Pathology | Alexander Quaas
Gastrointestinal Cancer Group Cologne (GCGC)
From: Becker et al. Ann Surg 2011 or Becker et al. Cancer 2003
Grade
Description
1a
No residual tumor / tumor bed
1b
< 10% residual tumor / tumor bed
2
10-50% residual tumor / tumor bed
3
> 50% residual tumor / tumor bed