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Preoperative

Chemoradiation

Planned Esophagectomy

• Walsh et al – 1996 (Trimodality)

Phase III Trial Chir

±

Preop RTCT

• CROSS - 2015 (Trimodality)

Phase III Trial Chir Preop RTCT

• POET - 2009 (Trimodality)

Phase III Trial Chir + Preop CT

±

RT

• Urba et al – 2001 (Trimodality)

Phase III Trial Chir

±

Preop RTCT

• Burmeister et al – 2005 (Trimodality)

Phase III Trial Chir

±

Preop RTCT

• Tepper et al – 2008 (Trimodality)

Phase III Trial Chir

±

Preop RTCT

Preoperative

Chemoradiation

Planned Esophagectomy

• FFCD 9901 - 2014 (Trimodality)

Phase III Trial Chir

±

Preop RTCT

±