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Pre-operative chemoradiotherapy is feasible and safe:

early results from the TOPGEAR study

PART 1 (n=120):

• Grade ≥3 anastomotic leakage:

5.6% vs. 7.8%

• Grade ≥3 intra-abdominal sepsis:

Leong et al. BMC Cancer 2015, ECC Vienna 2015

7.4% vs. 5.9%