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Summary (2): efficacy
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Gastric cancer is relatively radioresistant and has a high
tendency to recur locoregionally after surgery
•
To obtain disease control, high radiation doses (>40-50 Gy)
are required
•
Radiotherapy alone in the pre- or post-operative setting is
well-tolerated, but shows limited benefit
•
Chemoradiotherapy shows the largest benefit
•
Pre-operative chemoradiotherapy has advantages over
post-operative treatment