920 / 1084
Accumulated dose
a case study (1)
•
3 different scenario’s will be illustrated
:
•
(
1
) Accumulate (physical) dose of primary and re-irradiation
Evaluate the dose received to different regions of the spinal cord,
correct for EQD2/2
Define tolerance dose for re-irradiation to these different regions
using EQD2/2, translate to physical dose, and use this in the
optimization algorithm
•
(
2
) Accumulate dose distribution of primary and re-irradiation,
but rescaled to EQD2/2 to assess dose to spinal cord.
•
(
3
) Recalculate both dose distributions with EQD2/2 in spinal
cord only, physical dose everywhere else, and accumulate.
•
… Recalculate dose distribution with EQD2/2 in all OARs
and
PTV, and accumulate ... include recovery factors …
re-irradiation 2017 - D. Verellen