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Accumulated dose

a case study (2)

Treatment approach re-irradiation:

Previous irradiation (TomoTherapy):

30 x 2.13 Gy = 63.9 Gy

Re-irradiation (VERO):

Mediastinal:

10 x 4 Gy = 40 Gy

Right Middle Lobe:

10 x 5 Gy = 50 Gy

Assumption

s:

Acute toxicity for lungs and oesophagus less relevant considering gap

of 1 year.

For both oesophagus and lungs an α/β = 3 is assumed for late toxicity

Lungs: V

20

< 40%

Oesophagus: D

2%

< 68 Gy (ie maximum 10Gy with re-irradiation)

re-irradiation 2017 - D. Verellen