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The

first

chemotherapeutic agent against mGC was

5-FU

, either

alone

or

in combination

with various reagents (

FAM, FAMTX

)

In the late 1990s, a randomized trial showed that

epirubicin, cisplatin and venous infusion

of 5-FU

(

ECF

) was better than FAMTX

03/28/2017