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Case 1:

patient with stage N+ (D1) disease

A 78-year-old man was shown to have a prostate-

specific antigen (PSA) level of 18 ng/mL in a

routine evaluation.

His physical exam was normal and the digital rectal

examination revealed a slightly enlarged prostate

(87 cc by transrectal ultrasound).

Prostatic biopsy revealed a Gleason score 8 (4 + 4)

adenocarcinoma in 7 of 12 specimens.

His past medical history was significant for

systemic hypertension and dyslipidemia.