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Method
Margin
(AMC)
Extra
treatment time
Imaging dose
Corretable? Relevant
anatomical
information
Bone match
10 mm
2-3 minutes
(3cGY*2) High Possible
-
Offline fiducial
PI
8 mm
0 minutes
No
-
+
Online fiducial
PI
7 mm
1-3 minutes
Very low (kV) to
high (MV)
Correctable in
case of PI
+
Online CBCT 7 mm
1-3 minutes
0.4-3.5 cGy/scan Partly
+++
If there is a balance with the used margin:
1. LC is about the same for the all different procedures
2. Toxicity probably lowest with online IGRT