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Reviewer Name:
Melissa Phillips
Email:
melissa.phillips@nist.govOrganization:
NIST
Method Reviewed:
TUR‐01
Method Title:
Curcuminoids in Turmeric Roots and Supplements: Method Optimization and
Validation
Applicable SMPR
2016.003
Summary of Method:
A methanol extraction followed by LC‐absorbance for determination of CUR, BDMC,
and DMC in turmeric materials. A full method validation is described including
optimization of multiple experimental conditions.
1. Does the Applicability of the
Method Support the Applicability
of the SMPR? If not, please explain
what is missing.
Yes
2. Does the analytical technique(s)
used in the method meet the
SMPR? If not, please specify how it
differs from what is stated in the
SMPR.
Yes
3. Are the definitions specified in
the SMPR used and applied
appropriatly in the method? If no,
please indicate how the terms are
used.
Yes
4. Does the method, as written,
contain all appropriate precautions
and warnings related to the
method's regaents, components,
instrumentation, or method steps
that may be hazardous? If no,
please suggest wording or
option(s).
No safety information is included. Could potentially include a statement regarding
flammability of solvents, acidity of mobile phase, as well as use of elevated column
temperature, but this is not critical.
1. Are the definitions specified in
the SMPR used and applied
appropriately in the supporting
documentation (manuscripts,
method studies, etc…)? If not,
please explain the differences and
if the method is impacted by the
difference.
Yes
I. Summary
II. Review of the Method Only
III. Review of Information in Support of the Method
General Information