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AOAC Stakeholder Panel on Agent Detection Assays:
Stakeholder Panel Meeting
Meeting Minutes
Thursday, March 10, 2015; 2:00 p.m. – 3:00 p.m. EST
Attendees
Panel Members
(Present during all or part of the
meeting)
:
AOAC Staff
(Present during all or part of the meeting)
:
Eileen Ostlund, USDA (Chair)
Linda Beck, Naval Surface Warfare Center
Ryan Cahall, Censeo Insight
Joan Gebhardt, NMRC
Pejman Naraghi-Arani, LLNL
Ann Powers, CDC
Darci Smith, SRI
Scott Coates
Christopher Dent
Krystyna McIver
Meeting Minutes
I.
Welcome and Introductions
All participants were welcomed and roll call was taken.
II.
Review of Last Meeting and Fitness for Purpose Statement
Coates reviewed the Fitness for Purpose statement and explained that it had led him to draft SMPRs
for VEE and EEV. EEV SMPR is for identification of EEV, WEE and VEE. The VEE-only SMPR is for
confirmation methods. For identification methods Probability of Identification (POI) is used instead
of Probability of Detection (POD). It would challenge the method with a number of viruses to
determine when VEE is there and when it is not.
Coates then asked the group for ideas on the best approach for proceeding with SMPRs for VEE/EEV.
Group members said that it would be a great deal of time and effort to take a combined approach.
DoD representatives advised that they would be satisfied with one just for VE E – even that alone is
complex. Ostlund agreed and stated that the group will focus on an SMPR for VEE only, with the
potential to look at the others once VEE is complete.
The group then discussed development of SMPRs for identification, detection, or both. The primary
need is to know which strain of the virus is present, so the initial focus will be on identification of
VEE. Cahall advised that non pathogenic strains are of little interest.
III.
SMPR Development
The group proceeded to modify a draft SMPR. Since the scope is limited to VEE, WEE and EEE were
removed.