Slide 1

Background

Collagen

• Main structural protein in the extracellular space in various connective

tissues in animals.

• Primary component of connective tissue

• Most abundant protein in mammals (~25% to 35% of protein content).

• Over 30 “Types”:

1. Fibrillar (Types I, II, III, V, XI)

2. non-fibrillar (all the rest) .

Background

Collagen structure

Connects/supports organs &

tissues

(e. g.

skin

, bone, blood vessels,

tendons, muscles, and

cartilage

)