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Two Compartments Models
Deconvolution
Deconcolving the tissue TAC with the arterial input function, would result in a BF-scaled IRF:
There are different ways to perform the deconvolution step, and different assumptions that
can be made to model the obtained IRF and to calculate different parameters.
t
BF
Fieselman et al: “Deconvolution-Based CT and MR Brain Perfusion Measurement: Theoretical Model Revisited and Practical
Implementation Details”,
International Journal of Biomedical Images
(2011).