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GEC-ESTRO target definitions (2)

HR CTV:

whole cervix (assumed residual tumor)

− Persistent GTV

− Always whole cervix

− Presumed extracervical tumor extension:

− Residual clinically edematous zones

− Residual grey zones on MRI

− No safety margins are added

− Dose high enough to sterilize macroscopic tumor

IR CTV:

significant microscopic disease at BT

− Encompasses HR CTV

− Safety margins (5 – 15 mm) depending on tumor spread

LR CTV:

presumed treated with EBRT, not treated with BT

Haie-Meder C. et al. Radiother Oncol 2005.