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Pre-treatment ADC correlates with outcome?
In preparation.
Lambrecht M. et al. Radiother Oncol 2014.
Five studies failed to distinguish
patients with unfavourable
disease based on pretreatment
ADC.
Six studies found high pre-
treatment tumour ADC to be
predictive of poor outcome
following CRT.
The pre-treatment
ADC
thresholds appear to be fairly
concordant with primary ADC <
0.79–0.88 x 10
-3
mm
2
/s and nodal
ADC < 1.11–1.14 x 10
-3
mm
2
/s to
be predictive of
favourable
outcome.