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Treatment monitoring

Repeated imaging to assess changes in disease

RECIST -

Response Evaluation Criteria In Solid Tumors

Tumor volume may not reflect clonogens

Shrinkage depends on cell kill, inter-fraction

proliferation

and

cell clearance

Rel. volume

Time (days)

Tumor shrinkage in different cervical tumors

Phys. Med. Biol. 62 N107