Surgery vs. neoadjuvant chemotherapy + surgery
Pennathur et al, Lancet 2013
• Rationale: control early spread of systemic disease
• MAGIC study (Cunningham) may not be generalisable to all
esophageal adenocarcinoma (26% EGJ/adeno)
• Meta-analyses favor neoadjuvant chemotherapy over surgery
alone
EBRO
2017