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Page Background

Esophageal cancer:

Neo-adjuvant Chemoradiotherapy or Chemotherapy?

Stahl et al. J Clin Oncol 2009

N=126

T3-4 N0-1 M0

AC GEJ

Neo-adjuvant chemoradiotherapy:

PLF x2 + 30 Gy

+ Cisplatin 50 mg/m

2

d1,8 + etop 80 mg/m

2

d3-5

RESECTION

Primary endpoint: 3-year overall survival

R

A

N

D

O

M

Neo-adjuvant chemotherapy (PLF):

Cisplatin 50 mg/m

2

bi-wk + 5FU 2 g/m

2

wk x2.5

RESECTION

EBRO

2017