Chemoradiotherapy compensates for poor surgery?
EBRO
2017
Gastric cancer adjuvant chemoradiation
N 458
stage Ib-III
R0 resection
D2 node dissection
Adjuvant chemotherapy
XP (cisplatin (60 mg/m2 d1)+ capecitabine
(1000mg/m2 BD d1-14) 3-weekly x 6
Adjuvant chemoradiation
XP x 2 → XP-RT (45 Gy 25# capecitabine
825mg/m2 BD) → XP x 2
Primary endpoint:
Disease free survival
R
A
N
D
O
M
ARTIST Trial
Lee et al. J Clin Oncol 2012; Park et al. J Clin Oncol 2015