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RT versus concomitant CTRT

• Trials

12 eligible (1921 patients)

9 included (1764 patients, 1657 deaths)

• Overall survival

HR = 0.89 [0.81 – 0.98]

+4% @ 2 years, +2.2% @ 5 years

NTT : 25 @ 2 years, 45 @ 5 years

• Event free survival

HR = 0.84 [0.74 – 0.96]

+6% @ 2 years, +3.5% @ 5 years

Auperin Ann Oncol 2006