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RT versus concomitant CTRT
• Trials
•
12 eligible (1921 patients)
•
9 included (1764 patients, 1657 deaths)
• Overall survival
•
HR = 0.89 [0.81 – 0.98]
•
+4% @ 2 years, +2.2% @ 5 years
•
NTT : 25 @ 2 years, 45 @ 5 years
• Event free survival
•
HR = 0.84 [0.74 – 0.96]
•
+6% @ 2 years, +3.5% @ 5 years
Auperin Ann Oncol 2006