204 / 1983
ACCORD 12/0405-Prodige 2
Gerard JP, J Clin Oncol. 2010 Apr 1;28(10):1638-44
Cap45 Capox50
p value
pCR
13.9% 19.2% 0.09
Sphincter sparing
74.6% 75.4%
Local recurrence
6.1% 4.4%
Overall survival
87.6% 88.3%
Acute G3-4 diarrhoea 3.2% 12.6% <0.001