PORTEC-1
•
Role of RT in Stage I disease (no LND)
•
Whole pelvis RT vs. observation
•
Inclusion criteria
–
G1, deep (≥50%) invasion
(2009 Ib)
–
G2, superficial or deep invasion
(2009 Ia + Ib)
–
G3, superficial (<50%) invasion
(2009 Ia)
Creutzberg CL, et al. Lancet. 2000 22;355(9213):1404-11