534-535 / 1983
Case 1 Treatment:
Laperriere, RadiotherOncol 2002
Bleehen, BJC 1991
Walker, RedJ, 1979
•
Post-op RT
•
Meta-analysis: RR: 0.81
•
60Gy >
OS
45Gy (Bleehan)
•
Persistent failure from benefit of higher doses/ boosts/ etc.
•
But what margins ?
•
How do we define success in GBM radiotherapy?