634-635 / 1983
Case 3 Management
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Treatment:
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Optimal treatment for G3 oligo is (surgery), RT and chemo
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G3 ‘oligo’: RT + PCV >
OS
RT alone
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1p/19q is prognostic, as is IDH-1 mutation
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1p/19q is also predictive
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Unclear if there is a role for chemo in non-1p/19q co-deleted tumours
•
Prognosis ?
Cainrncross, JCO 2013
van den Bent, JCO 2013