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Case 4 Management
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Most likely to be grade 2 astrocytoma
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Bx would help
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Prognosis in LGG:
Pignatti, JCO 2002
Astrocytoma histology
Age >=40
Tumor >=6 cm
Tumor crossing
midline
Neurologic deficit
Risk Group Score
Median OS
Low risk
0 - 2
7.8 years
High risk
3 - 5
3.7 years
Prognosis in ‘Low risk’ group:
55 yr old, triple-neg
20mm, 4 LN+ve woman with breast cancer