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Case 6

Role of WBRT

Focal Rx +WBRT ~

OS

Focal Rx alone

Focal Rx +WBRT >

IntraCranProg

Focal Rx alone

Focal Rx +WBRT ~

TimePS2

Focal Rx alone

SRS + WBRT <

CogFunc

SRS Alone

Is WBRT better in a small subset of patients ?

Andrews Lancet 2004 (Single met; SRS + WBRT >

OS

SRS alone)

Sperduto RedJ 2014 (GPA 3.5 – 4; SRS + WBRT >

OS

SRS alone)

Ayoma JAMA 2015 (NSCLC; GPA 2.5 – 4; SRS + WBRT >

OS

SRS alone)