848 / 1983
Study (year) Populati
on
Standard RT High Dose
RT
Results
Beckendolf
(2011)
LR – IR
– HR
70 Gy
80 Gy
Better BFS
Peeters
(2006)
LR – IR
– HR
68 Gy
78 Gy
Better BFS in IR and HR
Kuban
(2008)
LR – IR -
HR
70 Gy
78 Gy
Better BFS
Zietman
(2008)
LR – IR 70.2 Gy
79.2 Gy
Better BFS in LR, strong
trend in IR
Pollack
(2002)
LR – IR -
HR
70 Gy
78 Gy
Better BFS in IR and HR
Tra
Which evidences for dose escalation?