Advanced Physics for Brachytherapy 2018

TAKE HOME MESSAGES

• Investigate your uncertainty budgets for your specific clinical workflows and report them

• Clinical impact depends on dose level (EQD2, a/b ) and shape of the dose-response curve

• Observed dose-response curves in the literature are subject to (unreported) uncertainties

• Uncertainty reduction can help in individual cases near OAR dose limits and below target planning aims