Advanced Physics for Brachytherapy 2018

TAKE HOME MESSAGES

• reducing random uncertainties can change the slope of the dose-response relationship observed in a patient cohort ➢ Online image-based treatment delivery verification (reduce time between treatment simulation and treatment) ➢ Advanced in vivo treatment dose verification • reduction of large systematic uncertainties should be a goal for OAR and target structures ➢ Contouring uncertainties ➢ Large dose calculation uncertainties (see Luc‘s presentation on clinical outcome vs. dose calculation algorithm) ➢ Systematic OAR filling changes during treatment (filling protocols!)