207_Combined course Presentations

SCLC/LCNEC: State of the art treatment

 Platinum (either cis or carbo) combination chemotherapy (i.e cis/carbo- etoposide) x 4-6 courses q 3 weeks “standard of care” 1 st line therapy for both LD and ED

 Combined chemotherapy and thoracic radiotherapy (preferably early concurrent) standard of care for LD

 Possible role of upfront surgery in very limited disease

 Second line therapy: Topotecan o CAV or PE-rechallenge based on treatment-free interval (refractory vs sensitive disease)

 PCI for pts with both LD or ED with good response to 1 st line therapy

Thoracic irradiation in ED ?

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