207_Combined course Presentations

National or institutional molecular screening programs in breast cancer and other advanced solid tumors predictive biomarker

Institution or National Program Vanderbilt-Ingram Cancer Center

Platform

Cancer(s)

Archival vs Biopsy

Timeframe

Additional Details

SNaPshot

NSCLC, melanoma, and breast

Archived Ongoing

SNaPshot profiling of ~40 mutations in NSCLC and melanoma. Recently launched “PI3K” panel for breast cancer. Plan to perform whole exome sequencing for 100 patients per year. Customized Sequenom panel (~277 mutations in 25 genes). Plan to integrate NGS technology in near future.

Michigan University Illumina HiSeq Solid Tumors

Fresh Biopsies

Ongoing

Princess Margaret Hospital

Sequenom Breast, CRC,

Archival

1Q2012

Ovarian, NSCLC, and phase I