Physics Bucharest 2017

Intra-operative electrons: ELIOT trial

• ELIOT system : single dose 21Gy intra-operative electrons immediately post-operatively pioneered in Milan

• RCT of breast EBRT vs. ELIOT shows higher local cancer recurrence with ELIOT

• EBRT 5 year recurrence 0.4% • ELIOT 5 year recurrence 4.4%

• Only recommended in clinical trials with small tumours

• Veronesi et al. Lancet Oncology (2013) 14: 1269