Physics Bucharest 2017

6/3/2017

The inverse problem

Optimization can be based on a ‘ Cost Function ’ - a figure of merit based on the specification for target and sensitive organ dose requirement.

- Clearly there may be many terms for the target and each OAR, and there may be more than one minimum

ESTRO physics course 2017

25

What will you minimise for PTV?

A. Dose to PTV? B. Mean Dose to PTV? C. Dose difference to prescription dose?

33% 33% 33%

Dose to PTV?

Mean Dose to PTV?

Dose difference to pre...