Physics Bucharest 2017

Breast cancer

Scientific evidence: 3 Randomized controlled trials

Study

Significant Endpoints

n IMRT Non- IMRT

P-value

Donovan R&O 2007

Change in breast appearance (serial photographs)

306 40% 58% 0,008

Pignol Breast 2008

Moist desquamation

351 31% 48% 0,002

Evidence

Mukesh JCO 2013

Teleangiectasia (grade 2-3) Cosmesis (poor)

1145 8% 12%

14% 22%

0,02 0,03

(& comparative case studies)

31