Physics Bucharest 2017

Prostate cancer

Scientific evidence: No RCT; many comparative studies Consistent results with :  ↓ acute and late GI toxicity  =/↓ acute and = late GU toxicity  ↑ biochemical control with dose-escalation

1751 pts

Evidence

75.6 Gy

< 72 Gy

81 Gy IMRT

Late Grade ≥2 rectal toxicities

Zelefsky IJROBP 2008

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