SPSFAM Heavy Metals ERP Book

AOAC Expert Review Panel for Heavy Metals 

ER 7 yes. 1. Instrument setup – add paragraph on instrument tuning. 2.LOD/LOQ needs clarification.  Report LOQ using multiplication factor 10 instead of FDA factor 30 to align with AOAC. o Text in  the caption of Table 2016.04A and footnotes changed to include AOAC calculation. 3.Analytical  range should be included in method. o Added at the end of Calculation section. 4.Robustness  data for mobile phase pH range. No significant shifts we noted at pH range 7.75 to 8.75.  5.recautionary statement needed around pH and co‐elution and check reagents for  contamination prior to use. A note was added at the end of the QC Elements section. 6. nclude  acceptable range Arsenate contamination in the phosphate buffer. An acceptable concentration  of arsenic in the phosphate buffer was added in the Reagents and Standards section, E(h). 7. ER 8 request to determine LOQ using factor 10 instead of 30 has been incorporated into the edits Has this method received any additional recognitions? ER 1 None that I am aware of ER 2 Not I am aware of.  ER 3 I don't think so. ER 4 NOT SURE ER 5 no evidence was provided in the supporting document ER 6 Not aware of any ER 7 I am not aware of any additional recognition of the method. ER 8 no, not aware of any Please cite the OMA Method, Number, etc. AOAC Official Method 2016.04 Four Arsenic Species in  Fruit Juice High‐Performance Liquid Chromatography‐ Inductively Coupled Plasma‐Mass Spectrometry 

ER 1 ER 2 ER 3 ER 4 ER 5 ER 6

2016.04

OMA Method 2016.04 AOAC OMA 2016.04

OMA 2016.04

2016.04

ER 7 AOAC Official Method 2016.04 Four Arsenic Species in Fruit Juice High‐Performance Liquid  Chromatography‐ Inductively Coupled Plasma‐Mass Spectrometry First Action 2016 ER 8 AOAC 2016.04 If there are methods published in the JAOAC  for this method, please cite the references: SLV:  S. Conklin, K. Kubachka and  N. Shockey. J AOAC International, VOL. 99, NO. 4, 2016  p1125‐ 1133

MLT: K. Kubachka, D. Heitkemper and S. Conklin.  J AOAC International, VOL. 100, NO. 4, 2017   p1077‐1085

ER 1

K.Kubathka, D.T.Heitkemper, S.Conklin. J AOAC Int., 2017, 100, 1077‐1085. 

ER 2

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