SPSFAM Heavy Metals ERP Book

Stakeholder Panel for Strategic Foods and Analytical Methods AOAC EXPERT REVIEW PANEL FOR HEAVY METALS

TABLE OF CONTENTS

I. ABOUT AOAC OF F ICAL METHODS OF ANALYSIS ™....................................................................................... 3 II. AGENDA............................................................................................................................................................. 7 III. AOAC INT ERNATIONAL VOLUNTEER CONFLICT OF INTEREST, STATEMENT OF POLICY ........................................ 9 IV. AOAC IN TERNATIONAL ANT I TRUST POLICY STATEMENT AND GUIDELINES .................................11 V. AOAC IN TERNATIONAL POLICY ON THE USE OF THE ASSOC I ATION NAME, INITIALS, IDENTIFYING I NSIGNIA, LETTERHEAD, AND BUSINESS CARDS ................................................................................................. 15 VI. MEETING AND METHOD REVIEW INFORMATION ...................................................................................... 19 VII. AOAC EXPERT REVIEW PANEL ORIENTA TI ON PRESENTATION ................................................................21 VIII. REVIEW FINAL ACTION REQUIREMENTS FOR FIRST ACTION OFFICIAL METHODS A. AOAC Official Method 2015.01 Heavy Metals in Food, Inductively Coupled Plasma–Mass Spectrometry, First Action 2015 ( HVYM-001 ) ...........................................................................43 I. AOAC SMPR 2012.007: Standard Method Performance Requirements for Heavy Metals in a Variety of Foods and Beverages.............................................................................. 51 II. Multi-laboratory Validation Report .............................................................................. 53 • Data Sheets (Weblinks) – Refer to Page 2 of Table of Contents III. ARTICLE: Determination of Heavy Metals in Food by Inductively Coupled Plasma–Mass Spectrometry: First Action 2015.01 ........................................................ 79 IV. Expert Review Panel Report (February 2015) ............................................................... 88 B. AOAC Official Method 2016.04: Four Arsenic Species in Fruit Juice, High-Performance Liquid Chromatography-Inductively Coupled Plasma-Mass Spectrometry, First Action 2016 ( ARS-02 ) .................................................................................................99 I. AOAC SMPR 2015.006: Standard Method Performance Requirements SM (SMPRs) for Quantitation of Arsenic Species in Selected Foods and Beverages ............................. 107 II. AOAC OMA 2016.04 Final Action Requirements – Method Author Response............109 • Data Sheets (Weblinks) – Refer to Page 2 of Table of Contents III. AOAC OMA 2016.04: Feedback – Manuscript Review.................................................111 IV. AOAC OMA 2016.04: Feedback – End Users................................................................113 V. AOAC OMA 2016.04 Revised Method Redline.............................................................115 VI. ARTICLE: Determination of Four Arsenic Species in Fruit Juice by High-Performance Liquid Chromatography-Inductively Coupled Plasma-Mass Spectrometry: Single-Laboratory Validation, First Action 2016.04 ............................. 131 VII. ARTICLE: Multi-laboratory Validation of First Action Method 2016.04 for Determination of Four Arsenic Species in Fruit Juice by High-Performance Liquid Chromatography–Inductively Coupled Plasma–Mass Spectrometry .......................... 141 VIII. Expert Review Panel Report (March 2016) ................................................................. 152