AOAC_SPDS_ERP_-_Set_3

1. Are the definitions specified in the SMPR used and applied appropriately in the supporting documentation (manuscripts, method studies, etc...)? If not, please explain the differences and if the method is impacted by the difference. 2. Is there information demonstrating that the method meets the SMPR Method Performance Requirements using the Reference Materials stated in the SMPR? If not, then specify what is missing and how this impacts demonstration of performance of the method. method performs within the SMPR Method Performance Requirements using the Reference Materials stated in the SMPR? If not, then specify what is missing and how this impacts demonstration of method performance. 3. Is there information demonstrating that the method performs within the SMPR Method Performance REquirements table specifications for all analytes in the SMPR applicability statement? If not, please specify what is missing and whether or not the method's applicability should be modified. 1. Based on the supporting information, were there any additional steps in the evaluation of the method that indicated the need for any additional precautionary statements in the method? 4. Is there information demonstrating that the

Yes. A single lab validation was done. Not all of the analytes in the SMPR were covered.

In the single lab validation three of the four reference materials were used. The supporting data demonstrates selectivity, repeatability, ruggedness and linearity. LOD and LOQ are mentioned, but no supporting data is provided. A few of the repeatability results were out of the specified range of the SMPR.

Yes, the data meets SMPR method performance requirements for three of four reference materials were used. No other matrices were used as outlined in the SMPR.

This method covers six of the seven catechins outlined in the SMPR. All of the others might be able to be detected with the exception of Theanine. Work would need to be done to show that they could be added to the analysis successfully.

A statement about chemical safety needs to be added at a minimum.